The current study aimed to examine the associations between the Big Five personality dimensions, aesthetic judgment styles, and art interest. Participants (N = 253) were university students in Tehran, Iran. All participants completed measures of personality, aesthetic Judgment styles, and general interest in art. Results suggested that Openness to Experience was related to advanced styles of art judgment and interest in art-related activities. Regression analyses showed that sex (β = .18, t = 3.18, p = .002), Emotional Stability (β = .14, t = 2.47, p = .01), Openness to Experience (β = .18, t = 3.14, p = .002), symbolic aesthetic judgment style (β = .31, t = 4.63, p < .001), and concrete aesthetic judgment style (β = -.19, t = -3.25, p = .001) significantly predicted art interest. The role of personality and individual difference constructs in aesthetic judgment and art interest is discussed and future directions are outlined.