Loscalzo and Giannini (Loscalzo, Y., & Giannini, M. . Studyholism or Study Addiction? A comprehensive model for a possible new clinical condition. In A. M. Columbus (Ed.), Advances in psychological research, (Vol. 125, pp. 19-37). Hauppauge, NY, USA: Nova Science) recently proposed a theoretical model for a new potential clinical condition: Studyholism, or obsession toward studying. This study aims to analyze the psychometric properties of the instrument that has been created based on their theory, namely the Studyholism Inventory (SI-10). The participants are 1296 Italian college students aged between 19 and 55 years. We analyzed its factor structure, as well as its convergent and divergent validity, and we proposed the cut-off scores of the SI-10. Moreover, we investigated some demographic and study-related differences in studyholism and study engagement and the correlations with academic indicators. The results showed that the SI-10 is a ten-item (2 fillers) and 2-factor instrument (GFI = .98, CFI = .97, RMSEA = .07) with good psychometric properties. The SI-10 could be used in future research to analyze the features and correlates of studyholism, and for both clinical and preventive purposes, pointing to favor students’ well-being and academic success.